Nease struggled with injuries and the Panthers narrowly fell to host Matanzas 17-14 last Friday night.
Preston Staples, who has been dealing with a knee injury, returned and finished 7 of 12 passing for 65 yards and three interceptions.
Star running back Jareem Westcott rushed for 82 yards on 19 carries for the Panthers. Standout tight end and LSU signee Zach Sheffer left with an injury during the game, and standout running back/receiver Ashton Wood did not play.
Nease (2-3) opens Region 4-6A play Friday night againt White (2-3, 1-0).